Effects of Qili Qiangxin capsules on NT-proBNP level and cardiac function in silicosis patients / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To investigate the effects of Qili Qiangxin capsules on the amino-terminal pro-brain natriuretic peptide (NT-proBNP) level and cardiac function in patients with silicosis.</p><p><b>METHODS</b>Hospitalized silicosis patients with heart failure were divided into treatment group (41 cases) and control group (30 cases) according to their own will. Both groups received comprehensive symptomatic treatment; in addition, the treatment group received Qili Qiangxin capsules. The treatment lasted 6 months. The observed items included NT-proBNP level, 6-minute walk test, ultrasonic cardiogram, and NYHA classification before and after treatment.</p><p><b>RESULTS</b>According to NYHA classification, the response rate was 29.27%in the treatment group and 10.00%in the control group; there was a significant difference between the two groups (P < 0.05). The average walk distance in the treatment group was increased from 150.96±73.12 m before treatment to 169.32±77.04 m after treatment, and the improvement was statistically significant (P < 0.05). The average NT-proBNP level in the treatment group was reduced from 1154.44 ± 480.79 ng/L before treatment to 494.49 ± 342.61 ng/L after treatment, and the reduction was statistically significant (P < 0.01). Left ventricular ejection fraction was significantly improved in the treatment group (P < 0.05).</p><p><b>CONCLUSION</b>Qili Qiangxin capsules in addition to comprehensive symptomatic treatment can significantly reduce NT-proBNP level and improve cardiac function in silicosis patients, and thereby improve patients' quality of life.</p>

Experience of peri-operation complication and their treatment in permanent cardic pacemaker implantation / 中国基层医药

Objective To clarify the experience of peri-operation complication, their prevention and treat-ment in permanent eardic pacemaker implantation. Methods Retrospective analysis of 52 patients with permanent eardic pacemaker implantation, 6 patients occurred peri-operation complications(11.5 %), including 1 patient with cardic arrest and 1 patient with ventricular fibrillation in operation, 1 patient with hamothorax and 1 patient with electrode move after operation,2 patients with bag haematoma. Results All the complication were correctly cured.Conclusion The three key ways to prevent and treat complication contain adequant preparation before operation,skillful technique in operation and active managment within peri-operation.